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Salk News


Philanthropic donations to Salk Institute exceed record-breaking $100M in FY21

LA JOLLA—The Salk Institute announced today that philanthropic donors gave more than $100 million to support bold scientific research in fiscal year 2021 (ending in June). The amount is a new record in philanthropic gifts for the Institute, eclipsing the previous record gift total in 2019 by more than $11 million.


Axel Nimmerjahn leads research team awarded $11 million by the U19 Team-Research BRAIN Circuit Program

LA JOLLA—Salk Associate Professor Axel Nimmerjahn is leading a research team that has been awarded $11.2 million by The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, an effort that aims to investigate overarching principles of brain circuit function, including sensation, perception, decision-making and motor control. Nimmerjahn will lead an interdisciplinary five-year project investigating how astrocytes, star-shaped cells in the brain, process and modulate signals from neurons to better understand overall brain function.


Salk Professor Janelle Ayres named inaugural recipient of the Salk Institute Legacy Chair

LA JOLLA—Professor Janelle Ayres has been recognized for her contributions and dedication to advancing science through research by being named the inaugural recipient of the Salk Institute Legacy Chair, effective July 1, 2021.


Salk promotes Diana Hargreaves to associate professor

LA JOLLA—The Salk Institute has promoted Diana Hargreaves to the rank of associate professor for her notable contributions in epigenetic regulation, which make specific regions of our DNA accessible to the machinery of cells. The promotion was based on recommendations by Salk faculty and nonresident fellows, and approved by President Rusty Gage and the Institute’s Board of Trustees.


Benefits of time-restricted eating depend on age and sex

LA JOLLA—Time-restricted eating (TRE), a dietary regimen that restricts eating to specific hours, has garnered increased attention in weight-loss circles. A new study by Salk scientists further shows that TRE confers multiple health benefits besides weight loss. The study also shows that these benefits may depend on sex and age.


Salk receives INSIGHT Into Diversity magazine’s 2021 Inspiring Programs in STEM Award

LA JOLLA—The Salk Institute’s Education Outreach program has received the 2021 Inspiring Programs in STEM Award from INSIGHT Into Diversity magazine, the largest and oldest diversity and inclusion publication in higher education. The Inspiring Programs in STEM Award honors colleges and universities that encourage and assist students from underrepresented groups to enter the fields of science, technology, engineering and mathematics (STEM). Salk will be featured, along with 78 other recipients, in the September 2021 issue of INSIGHT Into Diversity magazine.


Researchers identify neurons involved in overdose deaths

LA JOLLA—It’s long been known that opioid overdose deaths are caused by disrupted breathing, but the actual mechanism by which these drugs suppress respiration was not understood. Now, a new study by Salk scientists has identified a group of neurons in the brainstem that plays a key role in this process.


Salk Institute among cross-collaborative teams gifted $220 million by Wu Tsai Human Performance Alliance

LA JOLLA—A Salk Institute team led by Professor Satchin Panda, along with teams from five other organizations, have been awarded a total of $220 million by the Joe and Clara Tsai Foundation’s Human Performance Alliance, whose philanthropic investment aims to transform human health on a global scale through the discovery and translation of the biological principles underlying human performance.


Salk Professor and neuroscientist Kay Tye wins Blavatnik National Award for Young Scientists

LA JOLLA—Salk Professor Kay Tye has been named one of three winners of the prestigious Blavatnik National Awards for Young Scientists, one of the world’s largest unrestricted prizes for early-career researchers. Tye, the laureate in the Life Sciences category, will receive $250,000 for her trailblazing work in studying the neural circuits and behaviors related to anxiety and social interaction.


How plants quickly adapt to shifting environmental conditions

LA JOLLA—Scientists—and gardeners—have long known that plants grow taller and flower sooner when they are shaded by close-growing neighbors. Now, for the first time, researchers at the Salk Institute have shown the detailed inner workings of this process.


Mourning the loss of one of our colleagues

It is with heartfelt sorrow that we inform you of the death of a member of the Salk community, Swati Tyagi, PhD. Swati, a postdoctoral researcher in the Hetzer lab, was tragically killed yesterday when a person in a car struck her from behind while she was riding her bike. We offer our deepest condolences to her family, friends and coworkers at this difficult time.


How neurons get past “no”

LA JOLLA—When looking at a complex landscape, the eye needs to focus in on important details without losing the big picture—a charging lion in a jungle, for example. Now, a new study by Salk scientists shows how inhibitory neurons play a critical role in this process.


Salk Institute receives Charity Navigator’s highest rating for tenth consecutive time

LA JOLLA—For the tenth consecutive time, the Salk Institute has earned the highest ranking—4 out of 4 stars—from Charity Navigator, America’s largest independent charity and nonprofit evaluator. Only three percent of the roughly 10,000 nonprofits evaluated have achieved this recognition ten consecutive times. The coveted ranking indicates the Salk Institute has demonstrated strong financial health and commitment to accountability and transparency, outperforming most other charities in America in regard to executing best fiscal practices and carrying out its mission in a financially efficient way.


“Bad fat” suppresses killer T cells from attacking cancer

LA JOLLA—In order for cancer to grow and spread, it has to evade detection by our immune cells, particularly specialized “killer” T cells. Salk researchers led by Professor Susan Kaech have found that the environment inside tumors (the tumor microenvironment) contains an abundance of oxidized fat molecules, which, when ingested by the killer T cells, suppresses their ability to kill cancer cells. In a vicious cycle, those T cells, in need of energy, increase the level of a cellular fat transporter, CD36, that unfortunately saturates them with even more oxidized fat and further curtails their anti-tumor functions.


Research advances one step closer to stem cell therapy for type 1 diabetes

LA JOLLA—Type 1 diabetes, which arises when the pancreas doesn’t create enough insulin to control levels of glucose in the blood, is a disease that currently has no cure and is difficult for most patients to manage. Scientists at the Salk Institute are developing a promising approach for treating it: using stem cells to create insulin-producing cells (called beta cells) that could replace nonfunctional pancreatic cells.


Salk Fellows Program welcomes Talmo Pereira

LA JOLLA—The Salk Institute has appointed neuroscientist Talmo Pereira to the Salk Fellows Program, renewing the program’s commitment to supporting future intellectual leaders in the biological sciences.


New study shows how to boost muscle regeneration and rebuild tissue

LA JOLLA—One of the many effects of aging is loss of muscle mass, which contributes to disability in older people. To counter this loss, scientists at the Salk Institute are studying ways to accelerate the regeneration of muscle tissue, using a combination of molecular compounds that are commonly used in stem-cell research.


Salk scientists reveal role of genetic switch in pigmentation and melanoma

LA JOLLA—Despite only accounting for about 1 percent of skin cancers, melanoma causes the majority of skin cancer-related deaths. While treatments for this serious disease do exist, these drugs can vary in effectiveness depending on the individual.


Distinguished bioengineer Christian Metallo to join Salk as a full professor

LA JOLLA—The Salk Institute welcomes bioengineer Christian Metallo, who will join the Salk faculty as a full professor in July 2021. He is currently an associate professor of bioengineering at the University of California San Diego.


Transforming atmospheric carbon into industrially useful materials

LA JOLLA—Plants are unparalleled in their ability to capture CO2 from the air, but this benefit is temporary, as leftover crops release carbon back into the atmosphere, mostly through decomposition. Researchers have proposed a more permanent, and even useful, fate for this captured carbon by turning plants into a valuable industrial material called silicon carbide (SiC)—offering a strategy to turn an atmospheric greenhouse gas into an economically and industrially valuable material.