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Salk News


Simple method turns human skin cells into immune-fighting white blood cells

LA JOLLA—For the first time, scientists have turned human skin cells into transplantable white blood cells, soldiers of the immune system that fight infections and invaders. The work, done at the Salk Institute, could let researchers create therapies that introduce into the body new white blood cells capable of attacking diseased or cancerous cells or augmenting immune responses against other disorders.


Salk neuroscientist Charles Stevens receives NSF grant under BRAIN Initiative

LA JOLLA–Charles Stevens, a professor in the Salk Institute’s Molecular Neurobiology Laboratory, will receive one of 36 Early Concept Grants for Exploratory Research (EAGER) from the National Science Foundation to further research on how complex behaviors emerge from the activity of the brain.


Salk Institute continues campaign success, raising $68 million in 2014 fiscal year

LA JOLLA—The Salk Institute for Biological Studies celebrates another successful year of fundraising with nearly $68 million raised in fiscal year 2014 to support The Campaign for Salk, the Institute’s first-ever capital fundraising campaign.


Genetic signal prevents immune cells from turning against the body

LA JOLLA–When faced with pathogens, the immune system summons a swarm of cells made up of soldiers and peacekeepers. The peacekeeping cells tell the soldier cells to halt fighting when invaders are cleared. Without this cease-fire signal, the soldiers, known as killer T cells, continue their frenzied attack and turn on the body, causing inflammation and autoimmune disorders such as allergies, asthma, rheumatoid arthritis, multiple sclerosis and type 1 diabetes.


Single gene controls jet lag

LA JOLLA–Scientists at the Salk Institute for Biological Studies have identified a gene that regulates sleep and wake rhythms.


Stephen F. Heinemann, pioneering Salk neuroscientist, dies at 75

Stephen F. Heinemann, whose pioneering research on neurotransmitter receptors in the brain helped lay the groundwork for understanding diseases of the brain, died August 6 of complications of kidney failure at Vibra Hospital in San Diego, California. He was 75.


“Glee” star Matthew Morrison headlines Symphony at Salk, August 23

LA JOLLA–Tickets are on sale now for the Salk Institute’s 19th Annual Symphony at Salk, one of the summer’s premiere events, taking place on Saturday, August 23. The annual musical affair features the highly regarded San Diego Symphony along with Emmy, Tony and Golden Globe-nominated star Matthew Morrison.


Salk researcher Tony Hunter to receive 2014 Royal Medal in biological sciences

LA JOLLA–Salk Institute professor Tony Hunter has been awarded the 2014 Royal Medal for biological sciences by the Royal Society, a fellowship of some of the world’s most eminent scientists based in the United Kingdom.


Salk scientists uncover new clues to repairing an injured spinal cord

LA JOLLA—Frogs, dogs, whales, snails can all do it, but humans and primates can’t. Regrow nerves after an injury, that is—while many animals have this ability, humans don’t. But new research from the Salk Institute suggests that a small molecule may be able to convince damaged nerves to grow and effectively rewire circuits. Such a feat could eventually lead to therapies for the thousands of Americans with severe spinal cord injuries and paralysis.


Analysis of African plant reveals possible treatment for aging brain

LA JOLLA—For hundreds of years, healers in São Tomé e Príncipe—an island off the western coast of Africa—have prescribed cata-manginga leaves and bark to their patients. These pickings from the Voacanga africana tree are said to decrease inflammation and ease the symptoms of mental disorders.


Memory relies on astrocytes, the brain’s lesser-known cells

LA JOLLA—When you’re expecting something—like the meal you’ve ordered at a restaurant—or when or when something captures your interest, unique electrical rhythms sweep through your brain.


New gene discovered that stops the spread of deadly cancer

LA JOLLA—Scientists at the Salk Institute have identified a gene responsible for stopping the movement of cancer from the lungs to other parts of the body, indicating a new way to fight one of the world’s deadliest cancers.


One injection stops diabetes in its tracks

LA JOLLA—In mice with diet-induced diabetes—the equivalent of type 2 diabetes in humans—a single injection of the protein FGF1 is enough to restore blood sugar levels to a healthy range for more than two days. The discovery by Salk scientists, published today in the journal Nature, could lead to a new generation of safer, more effective diabetes drugs.


No extra mutations in modified stem cells, study finds

LA JOLLA—The ability to switch out one gene for another in a line of living stem cells has only crossed from science fiction to reality within this decade. As with any new technology, it brings with it both promise—the hope of fixing disease-causing genes in humans, for example—as well as questions and safety concerns. Now, Salk scientists have put one of those concerns to rest: using gene-editing techniques on stem cells doesn’t increase the overall occurrence of mutations in the cells. The new results were published July 3, 2014 in the journal Cell Stem Cell.


Salk Institute welcomes four new faculty

LA JOLLA—The Salk Institute is pleased to welcome a new full professor and three new assistant professors, all exceptional leaders in their respective fields. The new faculty will facilitate innovative and collaborative breakthroughs in understanding human health and disease.


Some stem cell methods closer to “gold standard” than others

LA JOLLA—Researchers around the world have turned to stem cells, which have the potential to develop into any cell type in the body, for potential regenerative and disease therapeutics.


First appointment in new Salk Fellows Program

LA JOLLA—The Salk has launched a new initiative called the Salk Fellows Program. The program brings scientists from broad disciplines to the Institute to trigger innovation and perpetuate the collaborative spirit of the Salk.


Conrad T. Prebys gives $25 million to Salk Institute to support scientific research

LA JOLLA—The Salk Institute for Biological Studies has received a $25 million gift from San Diego philanthropist and former Salk trustee Conrad T. Prebys to support cutting-edge biological research on a wide range of diseases.


Pedal the Cause funds local ground-breaking cancer research with inaugural grant awards

LA JOLLA—Pedal the Cause, the region’s only multiday cycling fundraiser where 100 percent of the net proceeds goes to support cancer research in San Diego, today announced five research projects funded by the inaugural 2013 event. The Pedal the Cause grants offer enough support for initial experiments, which will ideally lead to grants from federal sources and to large-scale studies.


Salk professor named grantee in new pancreatic cancer research program

LA JOLLA—Ronald M. Evans, director of the Gene Expression Laboratory at Salk and Howard Hughes Medical Institute investigator, is one of three scientists chosen to receive $5 million in research funding as part of The Lustgarten Foundation’s new “Distinguished Scholars” program, which recognizes individuals who have made outstanding achievements in research to focus their efforts on finding a cure for pancreatic cancer.