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Salk News


More than 3,000 epigenetic switches control daily liver cycles

LA JOLLA, CA—When it’s dark, and we start to fall asleep, most of us think we’re tired because our bodies need rest. Yet circadian rhythms affect our bodies not just on a global scale, but at the level of individual organs, and even genes.


Salk scientists develop faster, safer method for producing stem cells

LA JOLLA, CA—A new method for generating stem cells from mature cells promises to boost stem cell production in the laboratory, helping to remove a barrier to regenerative medicine therapies that would replace damaged or unhealthy body tissues.


Two more Salk scientists elected as AAAS Fellows

LA JOLLA,CA—Salk faculty members Joseph Ecker and Joseph Noel have been named as 2012 Fellows by the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society and the publisher of the journal Science. Election as an AAAS Fellow is among the highest honors in American science and scholars are selected by their peers for “scientifically or socially distinguished efforts to advance science or its applications,” according to election administrators.


Salk faculty members honored as recipients of new endowed chairs

LA JOLLA,CA—The Salk Institute announced today that professors Edward M. Callaway and Joseph Noel have been appointed to endowed chairs in acknowledgment of their outstanding contributions and dedication to scientific research.


Thomas D. Albright named president of Academy of Neuroscience for Architecture

LA JOLLA, CA—The first architecture critic may have been Goldilocks. She complained that some things were too big and some too small, while others were “just right.” Yet how do architects determine what is just right? And why do we feel instantly at home in some spaces, while never feeling right in others?


Salk study finds diabetes raises levels of proteins linked to Alzheimer’s features

LA JOLLA, CA—Growing evidence suggests that there may be a link between diabetes and Alzheimer’s disease, but the physiological mechanisms by which diabetes impacts brain function and cognition are not fully understood. In a new study published in Aging Cell, researchers at the Salk Institute for Biological Studies show, for the first time, that diabetes enhances the development of aging features that may underlie early pathological events in Alzheimer’s.


Aggressive brain tumors can originate from a range of nervous system cells

LA JOLLA, CA—Scientists have long believed that glioblastoma multiforme (GBM), the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. In a paper published October 18 in Science, however, researchers at the Salk Institute for Biological Studies have found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons.


Salk scientists pinpoint key player in Parkinson’s disease neuron loss

LA JOLLA, CA—By reprogramming skin cells from Parkinson’s disease patients with a known genetic mutation, researchers at the Salk Institute for Biological Studies have identified damage to neural stem cells as a powerful player in the disease. The findings, reported online October 17, 2013 in Nature, may lead to new ways to diagnose and treat the disease.


Cold viruses point the way to new cancer therapies

LA JOLLA, CA—Cold viruses generally get a bad rap—which they’ve certainly earned—but new findings by a team of scientists at the Salk Institute for Biological Studies suggest that these viruses might also be a valuable ally in the fight against cancer.


What can the water monster teach us about tissue regeneration in humans?

LA JOLLA, CA—Based on two new studies by researchers at the Salk Institute for Biological Studies, regeneration of a new limb or organ in a human will be much more difficult than the mad scientist and supervillain, Dr. Curt Connors, made it seem in the Amazing Spider-man comics and films.


Discovery of reprogramming signature may help overcome barriers to stem cell-based regenerative medicine

LA JOLLA, CA—Salk scientists have identified a unique molecular signature in induced pluripotent stem cells (iPSCs), “reprogrammed” cells that show great promise in regenerative medicine thanks to their ability to generate a range of body tissues.


A rare feat: Two scientists at Salk score NIH New Innovator awards

LA JOLLA, CA—The Salk Institute announced today that researchers Björn Lillemeier, and Axel Nimmerjahn, have been named recipients of the prestigious 2012 National Institutes of Health (NIH) Director’s New Innovator Award.


Discovery may help protect crops from stressors

LA JOLLA, CA—Scientists at the Salk Institute for Biological Studies have discovered a key genetic switch by which plants control their response to ethylene gas, a natural plant hormone best known for its ability to ripen fruit, but which, under stress conditions, can cause wilted leaves, premature aging and spoilage from over-ripening. The findings, published August 30 in Science magazine, may hold the key to manipulating plants’ ethylene on/off switch, allowing them to balance between drought resistance and growth and, therefore, decrease crop losses from drought conditions.


Daniel C. Lewis joins Salk Institute Board of Trustees

LA JOLLA, CA—The Board of Trustees of the Salk Institute for Biological Studies is pleased to announce that Daniel C. Lewis, a well-known leader in the global transportation, defense and aerospace industries, has been elected as the newest member.



Salk professors awarded chair appointments

LA JOLLA, CA—The Salk Institute is pleased to announce that professors E.J. Chichilnisky, Jan Karlseder, and Kuo-Fen Lee have each been selected as the recipient of an endowed chair to honor their consistent scientific excellence and support their biological research.


Planting the seeds of defense

LA JOLLA, CA—It was long thought that methylation, a crucial part of normal organism development, was a static modification of DNA that could not be altered by environmental conditions. New findings by researchers at the Salk Institute for Biological Studies, however, suggest that the DNA of organisms exposed to stress undergo changes in DNA methylation patterns that alter how genes are regulated.


Salk scientists discover molecular link between circadian clock disturbances and inflammatory diseases

LA JOLLA, CA—Scientists have known for some time that throwing off the body's circadian rhythm can negatively affect body chemistry. In fact, workers whose sleep-wake cycles are disrupted by night shifts are more susceptible to chronic inflammatory diseases such as diabetes, obesity and cancer.


Salk professor Terrence Sejnowski receives IEEE Frank Rosenblatt Award

LA JOLLA, CA—The Institute of Electrical and Electronics Engineers (IEEE), the world’s largest professional association dedicated to advancing technological innovation and excellence for the benefit of humanity, has awarded Terrence Sejnowski, professor and head of the Salk Institute’s Computational Neurobiology Laboratory, the 2013 IEEE Frank Rosenblatt Award.


Neurons derived from cord blood cells may represent new therapeutic option

LA JOLLA, CA—For more than 20 years, doctors have been using cells from blood that remains in the placenta and umbilical cord after childbirth to treat a variety of illnesses, from cancer and immune disorders to blood and metabolic diseases.