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Salk News


Country-pop superstar LeAnn Rimes to headline Symphony at Salk, August 25, one night only

LA JOLLA, CA—Multi-award-winning singer and country/pop music sensation LeAnn Rimes will perform with the San Diego Symphony and returning guest conductor Thomas Wilkins on August 25 for the 17th annual Symphony at Salk-A Concert under the Stars. The fundraiser supports the leading-edge biological research at the Institute and its award-wining community education programs.


Speeding up drug discovery with rapid 3D mapping of proteins

LA JOLLA, CA—A new method for rapidly solving the three-dimensional structures of a special group of proteins, known as integral membrane proteins, may speed drug discovery by providing scientists with precise targets for new therapies, according to a paper published May 20 in Nature Methods.


Researchers find a way to delay aging of stem cells

LA JOLLA, CA—Stem cells are essential building blocks for all organisms, from plants to humans. They can divide and renew themselves throughout life, differentiating into the specialized tissues needed during development, as well as cells necessary to repair adult tissue.


Salk study may offer drug-free intervention to prevent obesity and diabetes

LA JOLLA, CA—It turns out that when we eat may be as important as what we eat. Scientists at the Salk Institute for Biological Studies have found that regular eating times and extending the daily fasting period may override the adverse health effects of a high-fat diet and prevent obesity, diabetes and liver disease in mice.


Discovery of plant proteins may boost agricultural yields and biofuel production

LA JOLLA, CA—Scientists at the Salk Institute for Biological Studies and Iowa State University discovered a family of plant proteins that play a role in the production of seed oils, substances important for animal and human nutrition, biorenewable chemicals and biofuels.


Salk Institute named SDG&E 2012 Energy Champion

LA JOLLA, CA—San Diego Gas & Electric (SDG&E) named the Salk Institute for Biological Studies as an Energy Champion for their outstanding efforts in energy efficiency and conservation at an awards ceremony on May 10. The Institute is one of 13 local businesses recognized for “going above and beyond to save energy and money by taking advantage of the many rebates and incentives that are available through SDG&E’s energy-efficiency and demand response programs,” said Hal Snyder, vice president of customer solutions for SDG&E.


From feast to famine: A metabolic switch that may help diabetes treatment

LA JOLLA, CA—Humans are built to hunger for fat, packing it on during times of feast and burning it during periods of famine. But when deluged by foods rich in fat and sugar, the modern waistline often far exceeds the need to store energy for lean times, and the result has been an epidemic of diabetes, heart disease and other obesity-related problems.


Salk scientist elected to American Academy of Arts and Sciences

LA JOLLA, CA—Salk researcher Edward M. Callaway, a professor in the Systems Neurobiology Laboratories has been elected a Fellow of the American Academy of Arts and Sciences. Dr. Callaway shares the honor with some of the world’s most accomplished leaders from academia, business, public affairs, the humanities, and the arts.


Salk scientists discover how plants grow to escape shade

LA JOLLA, CA—Mild mannered though they seem, plants are extremely competitive, especially when it comes to getting their fair share of sunlight. Whether a forest or a farm, where plants grow a battle rages for the sun’s rays.


Qualcomm donates $1.5 million to Salk in honor of trucking pioneer

LA JOLLA, CA—In memory of Don Schneider, former president, CEO and chairman of Schneider National, Qualcomm has donated $1.5 million to establish the Don Schneider Qualcomm Innovation Fellowship at the Salk Institute. The fellowship will endow a postdoctoral position in Schneider’s name in perpetuity and enable the Salk Institute to continue hiring the world’s best scientists to conduct biological research that impacts humanity.


Sugar production switch in liver may offer target for new diabetes therapies

LA JOLLA, CA—In their extraordinary quest to decode human metabolism, researchers at the Salk Institute for Biological Studies have discovered a pair of molecules that regulates the liver’s production of glucose—the simple sugar that is the source of energy in human cells and the central player in diabetes.


Salk scientists redraw the blueprint of the body’s biological clock

LA JOLLA, CA—The discovery of a major gear in the biological clock that tells the body when to sleep and metabolize food may lead to new drugs to treat sleep problems and metabolic disorders, including diabetes.


Salk Institute announces faculty promotions

LA JOLLA, CA—Faculty members Reuben Shaw and Lei Wang, have been promoted to the position of Associate Professor at the Salk Institute after a rigorous evaluation process by Salk senior faculty, Non-Resident Fellows, and scientific peers. The career milestone distinguishes these two investigators as leading authorities in their respective disciplines who have made original, innovative and notable contributions to biological research.


Prestigious endowed chairs awarded to Salk scientists

The Salk Institute is pleased to announce that faculty members Geoffrey M. Wahl and Martyn Goulding were celebrated as the recipients of endowed chairs in recognition of their significant scientific accomplishments at a special reception on March 29. Joseph Ecker, professor in Salk’s Plant Molecular and Cellular Biology Laboratory, who was named holder of the International Council Chair in Genetics in September 2011, was also honored at the ceremony.


Salk scientists open new window into how cancers override cellular growth controls

LA JOLLA, CA—Rapidly dividing cancer cells are skilled at patching up damage that would stop normal cells in their tracks, including wear and tear of telomeres, the protective caps at the end of each chromosome.


Sending out an SOS: How telomeres incriminate cells that can’t divide

LA JOLLA, CA—The well-being of living cells requires specialized squads of proteins that maintain order. Degraders chew up worn-out proteins, recyclers wrap up damaged organelles, and-most importantly-DNA repair crews restitch anything that resembles a broken chromosome. If repair is impossible, the crew foreman calls in executioners to annihilate a cell. As unsavory as this last bunch sounds, failure to summon them is one aspect of what makes a cancer cell a cancer cell.


Discovery of brain’s natural resistance to drugs may offer clues to treating addiction

LA JOLLA, CA—A single injection of cocaine or methamphetamine in mice caused their brains to put the brakes on neurons that generate sensations of pleasure, and these cellular changes lasted for at least a week, according to research by scientists at the Salk Institute for Biological Studies.


Renato Dulbecco, Nobel Laureate and pioneering cancer researcher, dies at 97

LA JOLLA, CA—Renato Dulbecco, M.D., Nobel Prize winner and a global leader in cancer research passed away February 19 at his home in La Jolla. Born on February 22, 1914, he was just shy of his 98th birthday.


Salk researchers find new drug target for lung cancer

LA JOLLA,CA—Drugs targeting an enzyme involved in inflammation might offer a new avenue for treating certain lung cancers, according to a new study by scientists at the Salk Institute for Biological Studies.


Complex wiring of the nervous system may rely on just a handful of genes and proteins

LA JOLLA, CA—Researchers at the Salk Institute have discovered a startling feature of early brain development that helps to explain how complex neuron wiring patterns are programmed using just a handful of critical genes. The findings, published in Cell, may help scientists develop new therapies for neurological disorders, such as amyotrophic lateral sclerosis (ALS), and provide insight into certain cancers.