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Salk News


Salk Scientists Unlock Secret of Insulin Release

La Jolla, CA – A Salk Institute research team has made a discovery that provides valuable insight into a complication that is common among organ transplant patients and could eventually lead to new therapies for diabetes.


Salk Institute’s Ronald M. Evans Awarded 2004 Lasker Award For Basic Medical Research

La Jolla, CA – Ronald M. Evans, Ph.D. known for his discoveries of genetic switches that link hormones to gene control, is this year’s recipient of the highly prestigious 2004 Lasker Award for Basic Medical Research, the Albert and Mary Lasker Foundation announced today.


Puzzle of “French Paradox” Natural Product Solved

La Jolla, CA – Researchers at the Salk Institute have successfully bioengineered resveratrol synthase from chalcone synthase, a biosynthetic protein enzyme found in all higher plants. Their findings appear in the September issue of Chemistry & Biology.


Marathoning Mice Could Have Olympian Effects on Obesity

La Jolla, CA – A molecular switch known to regulate fat metabolism appears to prevent obesity and turns laboratory mice into marathon runners, a Salk Institute study has found.


Francis Harry Compton Crick 1916-2004

La Jolla, CA – Francis Harry Compton Crick, co-discoverer of the double helical genetic blueprint of life known commonly as DNA, died yesterday. He was 88 years old and a resident of La Jolla, Calif.


Inflammation’s Trigger Finger

La Jolla, CA – A molecule found in nearly all cells plays a vital role in kick-starting the production of key biological molecules involved in inflammation, a group of Salk Institute scientists has discovered. The finding, published in the June 25 issue of Science, may lead to new strategies for blocking the devastating inflammation that lies at the heart of autoimmune disorders such as multiple sclerosis, arthritis, lupus as well as some cancers.


New Findings Reopen Debate About Adult Stem Cell Plasticity

La Jolla, CA – Adult stem cells in the brain can change their destiny and become blood vessel cells instead of nerve cells, a Salk Institute study has found.


The Romeros to Headline Aug. 21 Symphony at Salk

La Jolla, CA – Known as the ‘Royal Family of the Guitar,’ the Del Mar-based Romeros will perform at the ninth annual Symphony at Salk, a benefit for the Salk Institute for Biological Studies (www.salk.edu) scheduled for Saturday, Aug. 21.


New Light on How the Brain Handles Brightness

La Jolla, CA – Studies by a Salk Institute research team on how we perceive the brightness of light may reveal how the brain is wired to handle the wide ranges of light stimulation we encounter every minute.


One Amino Acid Away from AIDS

La Jolla, CA – The ability of the AIDS virus to infect one species and bypass another may hinge on a single amino acid, a Salk Institute study has found. The work builds on the knowledge that HIV, the AIDS virus that infects humans, is relatively harmless to mice and even monkeys. The study furthers understanding of how HIV infects specific species while sparing others, and may help in the eventual development of novel drugs that halt the disease.


A New View of HIV

La Jolla, CA – Scientists will have a new view of how the AIDS virus (HIV) enters a target cell and begins its process of infection, thanks to a technique created by researchers at the Salk Institute.


Zeroing in on Stress Receptors Could Lead to Treatment of Heart Failure

La Jolla, CA – A hormone that helps the body adapt to stress may provide a key to designing treatments for congestive heart failure, according to a study by researchers at the Salk Institute for Biological Studies and the University of California, San Diego (UCSD) School of Medicine.


Hunter Receives Two Major Cancer Awards

La Jolla, CA – Tony Hunter, professor of molecular and cell biology at the Salk Institute, has received two major awards for cancer research.


It’s the Dosage: Salk Study Shows How Drugs of Abuse Work

La Jolla, CA – Researchers at the Salk Institute and the University of Geneva have discovered a novel mechanism to explain how the drug of abuse GHB affects the human nervous system. GHB is also known as the “date rape” drug.


Stem Cell Regulator Could Hold Key to Staving Off Age-related Brain Changes

La Jolla, CA – A brain-specific genetic switch protein known as a receptor has been found to control the fate of adult stem cells in the brain, according to a Salk Institute study.


Salk Study Uncovers New Information About Organ Placement

La Jolla, CA – A Salk Institute team of biologists, mathematicians, and physicists has uncovered a novel paradigm for cell communication that provides new insights into the complex question of how the body determines where organs are placed.


Waves of Nerve Cell Activity Create Sharp Vision in the Brain

La Jolla, CA – Nerve cells firing in spontaneous waves create the brain’s first sharp visual images during a short but critical phase of development, Salk Institute researchers have found. The study may lead to ways to better treat nerve cell injury and even treatments of diseases that occur in later life, like Parkinson’s.


Salk Institute Receives $7 Million Gift to Establish Neuroscience Center

La Jolla, CA – The Salk Institute has received a $7 million gift to establish a new center that will use computer-based computational biology methods to help unravel the complexities of the brain.


Salk Researcher named to Institute of Medicine

La Jolla, CA – Ronald Evans, the March of Dimes Chair in Developmental and Cell Biology at the Salk Institute, was named to the Institute of Medicine (IOM). Part of the U.S. National Academies, the IOM each year selects members who have made major contributions to furthering human health and advancing science.


Salk Institute Receives Record $30 Million Gift

La Jolla, CA – An anonymous donor has made a $30 million donation to the Salk Institute for Biological Studies, providing the largest single gift in the history of the Institute.