Assistant Professor
Molecular and Cell Biology Laboratory
Karasmanis, E.P., Reimer, J.M., Kendrick, A.A., Nguyen , K.H.V., Rodriguez, J.A., Truong, J.B., Lahiri, I., Reck-Peterson , S.L., Leschziner, A.E. Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge (2023) Nature Structural & Molecular Biology. 30:1357-1364. DOI: 10.1038/s41594-023-01069-6
Kendrick, A.A., Christensen, J.R. Bidirectional lysosome transport: a balancing act between ARL8 effectors. (2022) Nature Communications. 13(1):5261. DOI: 10.1038/s41467-022-32965-y
Christensen, J.R., Kendrick, A.A., Truong, J.B., Aguilar-Maldonado, A., Adani, V., Dzieciatkowska, M., Reck-Peterson, S.L. Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes. (2021) Elife. 10. DOI: 10.7554/eLife.74538
Humphries, B.A., Hwang, P.Y., Kendrick, A.A., Kulkarni, R.P., Pozzar, R.A., San Martin, R. Overstretched and overlooked: solving challenges faced by early-career investigators after the pandemic. (2021) Trends in Cancer. 7(10):879-882. DOI: 10.1016/j.trecan.2021.07.005
Kendrick, A.A., Dickey, A.M., Redwine, W.B., Tran, P.T., Vaites, L.P., Dzieciatkowska, M., Harper, J.W., Reck-Peterson, S.L. Hook3 is a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and KIF1C. (2019) Journal of Cell Biology. 218(9):2982-3001. DOI: 10.1083/jcb.201812170
Chi, Y.C., Rahkola, J.T., Kendrick, A.A., Holliday, M.J., Paukovich, N., Roberts, T.S., Janoff, E.N., Eisenmesser, E.Z. Streptococcus pneumoniae IgA1 protease: A metalloprotease that can catalyze in a split manner in vitro. (2017) Protein Science. 26(3):600-610. DOI: 10.1002/pro.3110
Kendrick, A.A., Schafer, J., Dzieciatkowska, M., Nemkov, T., D'Alessandro, A., Neelakantan, D., Ford, H.L., Pearson, C.G., Weekes, C.D., Hansen, K.C., Eisenmesser, E.Z. CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming. (2017) Oncotarget. 8(4):6742-6762. DOI: 10.18632/oncotarget.14272
Saeedi, B.J., Kao, D.J., Kitzenberg, D.A., Dobrinskikh, E., Schwisow, K.D., Masterson, J.C., Kendrick, A.A., Kelly, C.J., Bayless, A.J., Kominsky, D.J., Campbell, E.L., Kuhn, K.A., Furuta, G.T., Colgan, S.P., Glover, L.E. HIF-dependent regulation of claudin-1 is central to intestinal epithelial tight junction integrity. (2015) Molecular Biology of the Cell. 26(12):2252-62. DOI: 10.1091/mbc.E14-07-1194
Kendrick, A.A., Holliday, M.J., Isern, N.G., Zhang, F., Camilloni, C., Huynh, C., Vendruscolo, M., Armstrong, G., Eisenmesser, E.Z. The dynamics of interleukin-8 and its interaction with human CXC receptor I peptide. (2014) Protein Science. 23(4):464-80. DOI: 10.1002/pro.2430
Glover, L.E., Bowers, B.E., Saeedi, B., Ehrentraut, S.F., Campbell, E.L., Bayless, A.J., Dobrinskikh, E., Kendrick, A.A., Kelly, C.J., Burgess, A., Miller, L., Kominsky, D.J., Jedlicka, P., Colgan, S.P. Control of creatine metabolism by HIF is an endogenous mechanism of barrier regulation in colitis. (2013) Proceedings of the National Academy of Sciences of the United States of America. 110(49):19820-5. DOI: 10.1073/pnas.1302840110
Redzic, J.S., Kendrick, A.A., Bahmed, K., Dahl, K.D., Pearson, C.G., Robinson, W.A., Robinson, S.E., Graner, M.W., Eisenmesser, E.Z. Extracellular vesicles secreted from cancer cell lines stimulate secretion of MMP-9, IL-6, TGF-β1 and EMMPRIN. (2013) PLOS One. 8(8):e71225. DOI: 10.1371/journal.pone.0071225
Kendrick, A.A., Choudhury, M., Rahman, S.M., McCurdy, C.E., Friederich, M., Van Hove, J.L., Watson, P.A., Birdsey, N., Bao, J., Gius, D., Sack, M.N., Jing, E., Kahn, C.R., Friedman, J.E., Jonscher, K.R. Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation. (2011) Biochemical Journal. 433(3):505-14. DOI: 10.1042/BJ20100791
BS, Chemistry, University of Wroclaw
MS, Chemistry, University of Colorado, Denver
PhD, Structural Biology and Biochemistry, University of Colorado, Denver
Postdoctoral Fellow, Cellular and Molecular Medicine, University of California, San Diego