Assistant Professor
NOMIS Center for Immunobiology and Microbial Pathogenesis
Jaquish, A., Phung, E., Gong, X., Baldominos-Flores, P., Galvan-Pena, S., Bursulaya, I., Magill, I., , Bertrand, K., Chambers, C., Agudo, J., Mathis, D., Benoist, C., Ramanan, D. Expansion of mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis. (2024) bioRxiv. DOI: 10.1101/2024.07.09.602739
Ramanan, D., Chowdhary, K., Candéias, S.M., Sassone-Corsi, M., Gelineau, A., Mathis, D., Benoist, C. Homeostatic, repertoire and transcriptional relationships between colon T regulatory cell subsets. (2023) Proceedings of the National Academy of Sciences of the United States of America. 120(50):e2311566120. DOI: 10.1073/pnas.2311566120
Ramanan, D., Pratama, A., Zhu, Y., Venezia, O., Sassone-Corsi, M., Chowdhary, K., Galván-Peña, S., Sefik, E., Brown, C., Gélineau, A., Mathis, D., Benoist, C. Regulatory T cells in the face of the intestinal microbiota. (2023) Nature Reviews. Immunology. DOI: 10.1038/s41577-023-00890-w
Ramanan, D., Chowdhary, K., Candéias, S.M., Sassone-Corsi, M., Mathis, D., Benoist, C. Homeostatic, repertoire and transcriptional relationships between colon T regulatory cell subsets. (2023) bioRxiv. DOI: 10.1101/2023.05.17.541199
Wu, M., Zheng, W., Song, X., Bao, B., Wang, Y., Ramanan, D., Yang, D., Liu, R., Macbeth, J.C., Do, E.A., Andrade, W.A., Yang, T., Cho, H.S., Gazzaniga, F.S., Ilves, M., Coronado, D., Thompson, C., Hang, S., Chiu, I.M., Moffitt, J.R., Hsiao, A., Mekalanos, J.J., Benoist, C., Kasper, D.L. Microbiome induced complement synthesized in the gut protects against enteric infections. (2023) bioRxiv. DOI: 10.1101/2023.02.02.523770
Sassone-Corsi, M., Azriel, S., Simon, A., Ramanan, D., Ortiz-Lopez, A., Chen, F., Yissachar, N., Mathis, D., Benoist, C. Sequestration of gut pathobionts in intraluminal casts, a mechanism to avoid dysregulated T cell activation by pathobionts. (2022) Proceedings of the National Academy of Sciences of the United States of America. 119(41):e2209624119. DOI: 10.1073/pnas.2209624119
Yan, Y., Ramanan, D., Rozenberg, M., McGovern, K., Rastelli, D., Vijaykumar, B., Yaghi, O., Voisin, T., Mosaheb, M., Chiu, I., Itzkovitz, S., Rao, M., Mathis, D., Benoist, C. Interleukin-6 produced by enteric neurons regulates the number and phenotype of microbe-responsive regulatory T cells in the gut. (2021) Immunity. 54(3):499-513.e5. DOI: 10.1016/j.immuni.2021.02.002
Ramanan, D., Sefik, E., Galván-Peña, S., Wu, M., Yang, L., Yang, Z., Kostic, A., Golovkina, T.V., Kasper, D.L., Mathis, D., Benoist, C. An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint. (2020) Cell. 181(6):1276-1290.e13. DOI: 10.1016/j.cell.2020.04.030
Wong, S.Y., Coffre, M., Ramanan, D., Hines, M.J., Gomez, L.E., Peters, L.A., Schadt, E.E., Koralov, S.B., Cadwell, K. B Cell Defects Observed in Knockout Mice Are a Consequence of a Mutation Frequently Found in Inbred Strains. (2018) Journal of immunology. 201(5):1442-1451. DOI: 10.4049/jimmunol.1800014
Ramanan, D., Bowcutt, R., Lee, S.C., Tang, M.S., Kurtz, Z.D., Ding, Y., Honda, K., Gause, W.C., Blaser, M.J., Bonneau, R.A., Lim, Y.A., Loke, P., Cadwell, K. Helminth infection promotes colonization resistance via type 2 immunity. (2016) Science. 352(6285):608-12. DOI: 10.1126/science.aaf3229
Ramanan, D., Cadwell, K. Intrinsic Defense Mechanisms of the Intestinal Epithelium. (2016) Cell Host & Microbe. 19(4):434-41. DOI: 10.1016/j.chom.2016.03.003
Marchiando, A.M., Ramanan, D., Ding, Y., Gomez, L.E., Hubbard-Lucey, V.M., Maurer, K., Wang, C., Ziel, J.W., van Rooijen, N., Nuñez, G., Finlay, B.B., Mysorekar, I.U., Cadwell, K. A deficiency in the autophagy gene Atg16L1 enhances resistance to enteric bacterial infection. (2013) Cell Host & Microbe. 14(2):216-24. DOI: 10.1016/j.chom.2013.07.013
Zhang, Z., Wu, Y., Wang, Z., Dunning, F.M., Rehfuss, J., Ramanan, D., Chapman, E.R., Jackson, M.B. Release mode of large and small dense-core vesicles specified by different synaptotagmin isoforms in PC12 cells. (2011) Molecular Biology of the Cell. 22(13):2324-36. DOI: 10.1091/mbc.E11-02-0159
Postdoctoral Fellow, Harvard Medical School
PhD, Immunology and Inflammation, New York University
BS, Cell and Molecular Biology, Winona State University