Happonen, K.E., Burrola, P.G., Lemke, G. Regulation of brain endothelial cell physiology by the TAM receptor tyrosine kinase Mer. (2023) Communications Biology. 6(1):916. DOI: 10.1038/s42003-023-05287-y

Chen, D., Varanasi, S.K., Hara, T., Traina, K., Sun, M., McDonald, B., Farsakoglu, Y., Clanton, J., Xu, S., Garcia-Rivera, L., Mann, T.H., Du, V., Chung, H.K., Xu, Z., Tripple, V., Casillas, E., Ma, S., O'Connor, C., Yang, Q., Zheng, Y., Hunter, T., Lemke, G., Kaech, S.M. CTLA-4 blockade induces CD4 T cell IFNγ-driven microglial phagocytosis and anti-tumor function in glioblastoma. (2023) Immunity. DOI: 10.1016/j.immuni.2023.07.015

Huang, Y., Lemke, G. Adaptable toolbox to characterize Alzheimer's disease pathology in mouse models. (2022) STAR Protoc. 3(4):101891. DOI: 10.1016/j.xpro.2022.101891

Paolicelli, R.C., Sierra, A., Stevens, B., Tremblay, M.E., Aguzzi, A., Ajami, B., Amit, I., Audinat, E., Bechmann, I., Bennett, M., Bennett, F., Bessis, A., Biber, K., Bilbo, S., Blurton-Jones, M., Boddeke, E., Brites, D., Brône, B., Brown, G.C., Butovsky, O., Carson, M.J., Castellano, B., Colonna, M., Cowley, S.A., Cunningham, C., Davalos, D., De Jager, P.L., de Strooper, B., Denes, A., Eggen, B.J.L., Eyo, U., Galea, E., Garel, S., Ginhoux, F., Glass, C.K., Gokce, O., Gomez-Nicola, D., González, B., Gordon, S., Graeber, M.B., Greenhalgh, A.D., Gressens, P., Greter, M., Gutmann, D.H., Haass, C., Heneka, M.T., Heppner, F.L., Hong, S., Hume, D.A., Jung, S., Kettenmann, H., Kipnis, J., Koyama, R., Lemke, G., Lynch, M., Majewska, A., Malcangio, M., Malm, T., Mancuso, R., Masuda, T., Matteoli, M., McColl, B.W., Miron, V.E., Molofsky, A.V., Monje, M., Mracsko, E., Nadjar, A., Neher, J.J., Neniskyte, U., Neumann, H., Noda, M., Peng, B., Peri, F., Perry, V.H., Popovich, P.G., Pridans, C., Priller, J., Prinz, M., Ragozzino, D., Ransohoff, R.M., Salter, M.W., Schaefer, A., Schafer, D.P., Schwartz, M., Simons, M., Smith, C.J., Streit, W.J., Tay, T.L., Tsai, L.H., Verkhratsky, A., von Bernhardi, R., Wake, H., Wittamer, V., Wolf, S.A., Wu, L.J., Wyss-Coray, T. Microglia states and nomenclature: A field at its crossroads. (2022) Neuron. 110(21):3458-3483. DOI: 10.1016/j.neuron.2022.10.020

Huang, Y., Lemke, G. Early death in a mouse model of Alzheimer's disease exacerbated by microglial loss of TAM receptor signaling. (2022) Proceedings of the National Academy of Sciences of the United States of America. 119(41):e2204306119. DOI: 10.1073/pnas.2204306119

Jiménez-García, L., Mayer, C., Burrola, P.G., Huang, Y., Shokhirev, M.N., Lemke, G. The TAM receptor tyrosine kinases Axl and Mer drive the maintenance of highly phagocytic macrophages. (2022) Frontiers in Immunology. 13:960401. DOI: 10.3389/fimmu.2022.960401

Huang, Y., Happonen, K.E., Burrola, P.G., O'Connor, C., Hah, N., Huang, L., Nimmerjahn, A., Lemke, G. Microglia use TAM receptors to detect and engulf amyloid β plaques. (2021) Nature Immunology. DOI: 10.1038/s41590-021-00913-5

Nicolás-Ávila, J.A., Lechuga-Vieco, A.V., Esteban-Martínez, L., Sánchez-Díaz, M., Díaz-García, E., Santiago, D.J., Rubio-Ponce, A., Li, J.L., Balachander, A., Quintana, J.A., Martínez-de-Mena, R., Castejón-Vega, B., Pun-García, A., Través, P.G., Bonzón-Kulichenko, E., García-Marqués, F., Cussó, L., A-González, N., González-Guerra, A., Roche-Molina, M., Martin-Salamanca, S., Crainiciuc, G., Guzmán, G., Larrazabal, J., Herrero-Galán, E., Alegre-Cebollada, J., Lemke, G., Rothlin, C.V., Jimenez-Borreguero, L.J., Reyes, G., Castrillo, A., Desco, M., Muñoz-Cánoves, P., Ibáñez, B., Torres, M., Ng, L.G., Priori, S.G., Bueno, H., Vázquez, J., Cordero, M.D., Bernal, J.A., Enríquez, J.A., Hidalgo, A. A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart. (2020) Cell. DOI: 10.1016/j.cell.2020.08.031

Zagórska, A., Través, P.G., Jiménez-García, L., Strickland, J.D., Oh, J., Tapia, F.J., Mayoral, R., Burrola, P., Copple, B.L., Lemke, G. Differential regulation of hepatic physiology and injury by the TAM receptors Axl and Mer. (2020) Life Science Alliance. 3(8). DOI: 10.26508/lsa.202000694

Lemke, G., Silverman, G.J. Blood clots and TAM receptor signalling in COVID-19 pathogenesis. (2020) Nature Reviews. Immunology. DOI: 10.1038/s41577-020-0354-x

Diaz-Aparicio, I., Paris, I., Sierra-Torre, V., Plaza-Zabala, A., Rodríguez-Iglesias, N., Márquez-Ropero, M., Beccari, S., Huguet, P., Abiega, O., Alberdi, E., Matute, C., Bernales, I., Schulz, A., Otrokocsi, L., Sperlagh, B., Happonen, K.E., Lemke, G., Maletic-Savatic, M., Valero, J., Sierra, A. Microglia actively remodel adult hippocampal neurogenesis through the phagocytosis secretome. (2020) Journal of Neuroscience. DOI: 10.1523/JNEUROSCI.0993-19.2019

McShane, L., Tabas, I., Lemke, G., Kurowska-Stolarska, M., Maffia, P. TAM Receptors in Cardiovascular Disease. (2019) Cardiovascular Research. DOI: 10.1093/cvr/cvz100

Lemke, G. How macrophages deal with death. (2019) Nature Reviews. Immunology. DOI: 10.1038/s41577-019-0167-y

Lemke, G. Phosphatidylserine Is the Signal for TAM Receptors and Their Ligands. (2017) Trends in Biochemical Sciences. DOI: 10.1016/j.tibs.2017.06.004

Kurowska-Stolarska, M., Alivernini, S., Melchor, E.G., Elmesmari, A., Tolusso, B., Tange, C., Petricca, L., Gilchrist, D.S., Di Sante, G., Keijzer, C., Stewart, L., Di Mario, C., Morrison, V., Brewer, J.M., Porter, D., Milling, S., Baxter, R.D., McCarey, D., Gremese, E., Lemke, G., Ferraccioli, G., McSharry, C., McInnes, I.B. MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis. (2017) Nature Communications. 8:15877. DOI: 10.1038/ncomms15877

Savier, E., Eglen, S.J., Bathélémy, A., Perraut, M., Pfrieger, F.W., Lemke, G., Reber, M. A molecular mechanism for the topographic alignment of convergent neural maps. (2017) Elife. 6. DOI: 10.7554/eLife.20470

Tufail, Y., Cook, D., Fourgeaud, L., Powers, C.J., Merten, K., Clark, C.L., Hoffman, E., Ngo, A., Sekiguchi, K.J., O'Shea, C.C., Lemke, G., Nimmerjahn, A. Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia. (2017) Neuron. 93(3):574-586.e8. DOI: 10.1016/j.neuron.2016.12.021

Fourgeaud, L., Través, P.G., Tufail, Y., Leal-Bailey, H., Lew, E.D., Burrola, P.G., Callaway, P., Zagórska, A., Rothlin, C.V., Nimmerjahn, A., Lemke, G. TAM receptors regulate multiple features of microglial physiology. (2016) Nature. 532(7598):240-244. DOI: 10.1038/nature17630

Lemke, G. Adopting ALK and LTK. (2015) Proceedings of the National Academy of Sciences of the United States of America. 112(52):15783-4. DOI: 10.1073/pnas.1521923113

Miner, J.J., Daniels, B.P., Shrestha, B., Proenca-Modena, J.L., Lew, E.D., Lazear, H.M., Gorman, M.J., Lemke, G., Klein, R.S., Diamond, M.S. The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity. (2015) Nature Medicine. 21(12):1464-72. DOI: 10.1038/nm.3974

Fuhs, S.R., Meisenhelder, J., Aslanian, A., Ma, L., Zagorska, A., Stankova, M., Binnie, A., Al-Obeidi, F., Mauger, J., Lemke, G., Yates, J.R., Hunter, T. Monoclonal 1- and 3-Phosphohistidine Antibodies: New Tools to Study Histidine Phosphorylation. (2015) Cell. 162(1):198-210. DOI: 10.1016/j.cell.2015.05.046

Dransfield, I., Zagórska, A., Lew, E.D., Michail, K., Lemke, G. Mer receptor tyrosine kinase mediates both tethering and phagocytosis of apoptotic cells. (2015) Cell Death & Disease. 6:e1646. DOI: 10.1038/cddis.2015.18

Lemke, G., Lew, E.D. A ligand for ALK. (2015) Science Signaling. 8(360):fs2. DOI: 10.1126/scisignal.aaa5566

Lemke, G., Julius, D. Stephen F. Heinemann: A true original. (2014) Proceedings of the National Academy of Sciences of the United States of America. 111(40):14314-5. DOI: 10.1073/pnas.1416208111

Zagórska, A., Través, P.G., Lew, E.D., Dransfield, I., Lemke, G. Diversification of TAM receptor tyrosine kinase function. (2014) Nature Immunology. 15(10):920-8. DOI: 10.1038/ni.2986

Lew, E.D., Oh, J., Burrola, P.G., Lax, I., Zagórska, A., Través, P.G., Schlessinger, J., Lemke, G. Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities. (2014) Elife. 3. DOI: 10.7554/eLife.03385

Lemke, G. Biology of the TAM receptors. (2013) Cold Spring Harbor Perspectives in Biology. 5(11):a009076. DOI: 10.1101/cshperspect.a009076

Bhattacharyya, S., Zagórska, A., Lew, E.D., Shrestha, B., Rothlin, C.V., Naughton, J., Diamond, M.S., Lemke, G., Young, J.A. Enveloped viruses disable innate immune responses in dendritic cells by direct activation of TAM receptors. (2013) Cell Host & Microbe. 14(2):136-47. DOI: 10.1016/j.chom.2013.07.005

Carrera Silva, E.A., Chan, P.Y., Joannas, L., Errasti, A.E., Gagliani, N., Bosurgi, L., Jabbour, M., Perry, A., Smith-Chakmakova, F., Mucida, D., Cheroutre, H., Burstyn-Cohen, T., Leighton, J.A., Lemke, G., Ghosh, S., Rothlin, C.V. T cell-derived protein S engages TAM receptor signaling in dendritic cells to control the magnitude of the immune response. (2013) Immunity. 39(1):160-70. DOI: 10.1016/j.immuni.2013.06.010

Sullivan, B.M., Welch, M.J., Lemke, G., Oldstone, M.B. Is the TAM receptor Axl a receptor for lymphocytic choriomeningitis virus? (2013) Journal of Virology. 87(7):4071-4. DOI: 10.1128/JVI.03268-12

Burstyn-Cohen, T., Lew, E.D., Través, P.G., Burrola, P.G., Hash, J.C., Lemke, G. Genetic dissection of TAM receptor-ligand interaction in retinal pigment epithelial cell phagocytosis. (2012) Neuron. 76(6):1123-32. DOI: 10.1016/j.neuron.2012.10.015

Meertens, L., Carnec, X., Lecoin, M.P., Ramdasi, R., Guivel-Benhassine, F., Lew, E., Lemke, G., Schwartz, O., Amara, A. The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entry. (2012) Cell Host & Microbe. 12(4):544-57. DOI: 10.1016/j.chom.2012.08.009

Bauer, T., Zagórska, A., Jurkin, J., Yasmin, N., Köffel, R., Richter, S., Gesslbauer, B., Lemke, G., Strobl, H. Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis. (2012) Journal of Experimental Medicine. 209(11):2033-47. DOI: 10.1084/jem.20120493

Slavotinek, A.M., Chao, R., Vacik, T., Yahyavi, M., Abouzeid, H., Bardakjian, T., Schneider, A., Shaw, G., Sherr, E.H., Lemke, G., Youssef, M., Schorderet, D.F. VAX1 mutation associated with microphthalmia, corpus callosum agenesis, and orofacial clefting: the first description of a VAX1 phenotype in humans. (2012) Human Mutation. 33(2):364-8. DOI: 10.1002/humu.21658

Vacik, T., Lemke, G. Dominant-negative isoforms of Tcf/Lef proteins in development and disease. (2011) Cell Cycle. 10(24):4199-200. DOI: 10.4161/cc.10.24.18465

Wang, J., Zhang, H., Young, A.G., Qiu, R., Argalian, S., Li, X., Wu, X., Lemke, G., Lu, Q. Transcriptome analysis of neural progenitor cells by a genetic dual reporter strategy. (2011) Stem Cells. 29(10):1589-600. DOI: 10.1002/stem.699

Vacik, T., Stubbs, J.L., Lemke, G. A novel mechanism for the transcriptional regulation of Wnt signaling in development. (2011) Genes & Development. 25(17):1783-95. DOI: 10.1101/gad.17227011

Bevins, N., Lemke, G., Reber, M. Genetic dissection of EphA receptor signaling dynamics during retinotopic mapping. (2011) Journal of Neuroscience. 31(28):10302-10. DOI: 10.1523/JNEUROSCI.1652-11.2011

Rothlin, C.V., Lemke, G. TAM receptor signaling and autoimmune disease. (2010) Current Opinion in Immunology. 22(6):740-6. DOI: 10.1016/j.coi.2010.10.001

Lemke, G., Burstyn-Cohen, T. TAM receptors and the clearance of apoptotic cells. (2010) Ann. N. Y. Acad. Sci. 1209:23-9. DOI: 10.1111/j.1749-6632.2010.05744.x

Burstyn-Cohen, T., Heeb, M.J., Lemke, G. Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis. (2009) Journal of Clinical Investigation. 119(10):2942-53. DOI: 10.1172/JCI39325

Triplett, J.W., Owens, M.T., Yamada, J., Lemke, G., Cang, J., Stryker, M.P., Feldheim, D.A. Retinal input instructs alignment of visual topographic maps. (2009) Cell. 139(1):175-85. DOI: 10.1016/j.cell.2009.08.028

Stanojcic, M., Burstyn-Cohen, T., Nashi, N., Lemke, G., Sakic, B. Disturbed distribution of proliferative brain cells during lupus-like disease. (2009) Brain, Behavior, and Immunity. 23(7):1003-13. DOI: 10.1016/j.bbi.2009.05.061

Kang, K.H., Lemke, G., Kim, J.W. The PI3K-PTEN tug-of-war, oxidative stress and retinal degeneration. (2009) Trends in Molecular Medicine. 15(5):191-8. DOI: 10.1016/j.molmed.2009.03.005

Lemke, G. Isolation and analysis of the gene encoding peripheral myelin protein zero. (2008) Neuron. 60(3):403. DOI: 10.1016/j.neuron.2008.10.034

Kim, J.W., Kang, K.H., Burrola, P., Mak, T.W., Lemke, G. Retinal degeneration triggered by inactivation of PTEN in the retinal pigment epithelium. (2008) Genes & Development. 22(22):3147-57. DOI: 10.1101/gad.1700108

Pierce, A., Bliesner, B., Xu, M., Nielsen-Preiss, S., Lemke, G., Tobet, S., Wierman, M.E. Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration. (2008) Molecular Endocrinology. 22(11):2481-95. DOI: 10.1210/me.2008-0169

Lemke, G., Rothlin, C.V. Immunobiology of the TAM receptors. (2008) Nature Reviews. Immunology. 8(5):327-36. DOI: 10.1038/nri2303

Gallarda, B.W., Bonanomi, D., Müller, D., Brown, A., Alaynick, W.A., Andrews, S.E., Lemke, G., Pfaff, S.L., Marquardt, T. Segregation of axial motor and sensory pathways via heterotypic trans-axonal signaling. (2008) Science. 320(5873):233-6. DOI: 10.1126/science.1153758

Angelillo-Scherrer, A., Burnier, L., Lambrechts, D., Fish, R.J., Tjwa, M., Plaisance, S., Sugamele, R., DeMol, M., Martinez-Soria, E., Maxwell, P.H., Lemke, G., Goff, S.P., Matsushima, G.K., Earp, H.S., Chanson, M., Collen, D., Izui, S., Schapira, M., Conway, E.M., Carmeliet, P. Role of Gas6 in erythropoiesis and anemia in mice. (2008) Journal of Clinical Investigation. 118(2):583-96. DOI: 10.1172/JCI30375

Rothlin, C.V., Ghosh, S., Zuniga, E.I., Oldstone, M.B., Lemke, G. TAM receptors are pleiotropic inhibitors of the innate immune response. (2007) Cell. 131(6):1124-36. DOI: 10.1016/j.cell.2007.10.034

Roth, C., Rothlin, C., Riou, S., Raulet, D.H., Lemke, G. Stromal-cell regulation of natural killer cell differentiation. (2007) Journal of Molecular Medicine . 85(10):1047-56. DOI: 10.1007/s00109-007-0195-0

de Preux, A.S., Goosen, K., Zhang, W., Sima, A.A., Shimano, H., Ouwens, D.M., Diamant, M., Hillebrands, J.L., Rozing, J., Lemke, G., Beckmann, J.S., Smit, A.B., Verheijen, M.H., Chrast, R. SREBP-1c expression in Schwann cells is affected by diabetes and nutritional status. (2007) Molecular and Cellular Neurosciences. 35(4):525-34. DOI: 10.1016/j.mcn.2007.04.010

Seitz, H.M., Camenisch, T.D., Lemke, G., Earp, H.S., Matsushima, G.K. Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells. (2007) Journal of immunology. 178(9):5635-42.

Reber, M., Hindges, R., Lemke, G. Eph receptors and ephrin ligands in axon guidance. (2007) Advances in Experimental Medicine and Biology. 621:32-49. DOI: 10.1007/978-0-387-76715-4_3

Stephen, L.J., Fawkes, A.L., Verhoeve, A., Lemke, G., Brown, A. A critical role for the EphA3 receptor tyrosine kinase in heart development. (2007) Developmental Biology. 302(1):66-79. DOI: 10.1016/j.ydbio.2006.08.058

Kim, J.W., Lemke, G. Hedgehog-regulated localization of Vax2 controls eye development. (2006) Genes & Development. 20(20):2833-47. DOI: 10.1101/gad.1462706

Prasad, D., Rothlin, C.V., Burrola, P., Burstyn-Cohen, T., Lu, Q., Garcia de Frutos, P., Lemke, G. TAM receptor function in the retinal pigment epithelium. (2006) Molecular and Cellular Neurosciences. 33(1):96-108. DOI: 10.1016/j.mcn.2006.06.011

Sharif, M.N., Sosic, D., Rothlin, C.V., Kelly, E., Lemke, G., Olson, E.N., Ivashkiv, L.B. Twist mediates suppression of inflammation by type I IFNs and Axl. (2006) Journal of Experimental Medicine. 203(8):1891-901. DOI: 10.1084/jem.20051725

Caraux, A., Lu, Q., Fernandez, N., Riou, S., Di Santo, J.P., Raulet, D.H., Lemke, G., Roth, C. Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases. (2006) Nature Immunology. 7(7):747-54. DOI: 10.1038/ni1353

Shankar, S.L., O'Guin, K., Kim, M., Varnum, B., Lemke, G., Brosnan, C.F., Shafit-Zagardo, B. Gas6/Axl signaling activates the phosphatidylinositol 3-kinase/Akt1 survival pathway to protect oligodendrocytes from tumor necrosis factor alpha-induced apoptosis. (2006) Journal of Neuroscience. 26(21):5638-48. DOI: 10.1523/JNEUROSCI.5063-05.2006

Lemke, G. Neuregulin-1 and myelination. (2006) Sci. STKE. 2006(325):pe11. DOI: 10.1126/stke.3252006pe11

Radic, M.Z., Shah, K., Zhang, W., Lu, Q., Lemke, G., Hilliard, G.M. Heterogeneous nuclear ribonucleoprotein P2 is an autoantibody target in mice deficient for Mer, Axl, and Tyro3 receptor tyrosine kinases. (2006) Journal of immunology. 176(1):68-74.

Budagian, V., Bulanova, E., Orinska, Z., Duitman, E., Brandt, K., Ludwig, A., Hartmann, D., Lemke, G., Saftig, P., Bulfone-Paus, S. Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum. (2005) Molecular and Cellular Biology. 25(21):9324-39. DOI: 10.1128/MCB.25.21.9324-9339.2005

Lemke, G., Reber, M. Retinotectal mapping: new insights from molecular genetics. (2005) Annual Review of Cell and Developmental Biology. 21:551-80. DOI: 10.1146/annurev.cellbio.20.022403.093702

Mui, S.H., Kim, J.W., Lemke, G., Bertuzzi, S. Vax genes ventralize the embryonic eye. (2005) Genes & Development. 19(10):1249-59. DOI: 10.1101/gad.1276605

Angelillo-Scherrer, A., Burnier, L., Flores, N., Savi, P., DeMol, M., Schaeffer, P., Herbert, J.M., Lemke, G., Goff, S.P., Matsushima, G.K., Earp, H.S., Vesin, C., Hoylaerts, M.F., Plaisance, S., Collen, D., Conway, E.M., Wehrle-Haller, B., Carmeliet, P. Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy. (2005) Journal of Clinical Investigation. 115(2):237-46. DOI: 10.1172/JCI22079

Reber, M., Burrola, P., Lemke, G. A relative signalling model for the formation of a topographic neural map. (2004) Nature. 431(7010):847-53. DOI: 10.1038/nature02957

Chrast, R., Verheijen, M.H., Lemke, G. Complement factors in adult peripheral nerve: a potential role in energy metabolism. (2004) Neurochem. Int. 45(2-3):353-9. DOI: 10.1016/j.neuint.2003.09.011

Vaidya, A., Pniak, A., Lemke, G., Brown, A. EphA3 null mutants do not demonstrate motor axon guidance defects. (2003) Molecular and Cellular Biology. 23(22):8092-8.

Senderek, J., Bergmann, C., Stendel, C., Kirfel, J., Verpoorten, N., De Jonghe, P., Timmerman, V., Chrast, R., Verheijen, M.H., Lemke, G., Battaloglu, E., Parman, Y., Erdem, S., Tan, E., Topaloglu, H., Hahn, A., Müller-Felber, W., Rizzuto, N., Fabrizi, G.M., Stuhrmann, M., Rudnik-Schöneborn, S., Züchner, S., Michael Schröder, J., Buchheim, E., Straub, V., Klepper, J., Huehne, K., Rautenstrauss, B., Büttner, R., Nelis, E., Zerres, K. Mutations in a gene encoding a novel SH3/TPR domain protein cause autosomal recessive Charcot-Marie-Tooth type 4C neuropathy. (2003) American Journal of Human Genetics. 73(5):1106-19. DOI: 10.1086/379525

Verheijen, M.H., Chrast, R., Burrola, P., Lemke, G. Local regulation of fat metabolism in peripheral nerves. (2003) Genes & Development. 17(19):2450-64. DOI: 10.1101/gad.1116203

Zhu, D., Kennerson, M., Merory, J., Chrast, R., Verheijen, M., Lemke, G., Nicholson, G. Refined localization of dominant intermediate Charcot-Marie-Tooth neuropathy and exclusion of seven known candidate genes in the region. (2003) Neurogenetics. 4(4):179-83. DOI: 10.1007/s10048-003-0147-y

Lemke, G., Lu, Q. Macrophage regulation by Tyro 3 family receptors. (2003) Current Opinion in Immunology. 15(1):31-6.

Stefansson, H., Sigurdsson, E., Steinthorsdottir, V., Bjornsdottir, S., Sigmundsson, T., Ghosh, S., Brynjolfsson, J., Gunnarsdottir, S., Ivarsson, O., Chou, T.T., Hjaltason, O., Birgisdottir, B., Jonsson, H., Gudnadottir, V.G., Gudmundsdottir, E., Bjornsson, A., Ingvarsson, B., Ingason, A., Sigfusson, S., Hardardottir, H., Harvey, R.P., Lai, D., Zhou, M., Brunner, D., Mutel, V., Gonzalo, A., Lemke, G., Sainz, J., Johannesson, G., Andresson, T., Gudbjartsson, D., Manolescu, A., Frigge, M.L., Gurney, M.E., Kong, A., Gulcher, J.R., Petursson, H., Stefansson, K. Neuregulin 1 and susceptibility to schizophrenia. (2002) American Journal of Human Genetics. 71(4):877-92. DOI: 10.1086/342734

Mui, S.H., Hindges, R., O'Leary, D.D., Lemke, G., Bertuzzi, S. The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye. (2002) Development. 129(3):797-804.

Lu, Q., Lemke, G. Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family. (2001) Science. 293(5528):306-11. DOI: 10.1126/science.1061663

Lemke, G. Glial control of neuronal development. (2001) Annual Review of Neuroscience. 24:87-105. DOI: 10.1146/annurev.neuro.24.1.87

Syroid, D.E., Maycox, P.J., Soilu-Hänninen, M., Petratos, S., Bucci, T., Burrola, P., Murray, S., Cheema, S., Lee, K.F., Lemke, G., Kilpatrick, T.J. Induction of postnatal schwann cell death by the low-affinity neurotrophin receptor in vitro and after axotomy. (2000) Journal of Neuroscience. 20(15):5741-7.

Brown, A., Yates, P.A., Burrola, P., Ortuño, D., Vaidya, A., Jessell, T.M., Pfaff, S.L., O'Leary, D.D., Lemke, G. Topographic mapping from the retina to the midbrain is controlled by relative but not absolute levels of EphA receptor signaling. (2000) Cell. 102(1):77-88.

Kilpatrick, T.J., Ortuño, D., Bucci, T., Lai, C., Lemke, G. Rat oligodendroglia express c-met and focal adhesion kinase, protein tyrosine kinases implicated in regulating epithelial cell motility. (2000) Neurosci. Lett. 279(1):5-8.

Bertuzzi, S., Hindges, R., Mui, S.H., O'Leary, D.D., Lemke, G. The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain. (1999) Genes & Development. 13(23):3092-105.

Lu, Q., Gore, M., Zhang, Q., Camenisch, T., Boast, S., Casagranda, F., Lai, C., Skinner, M.K., Klein, R., Matsushima, G.K., Earp, H.S., Goff, S.P., Lemke, G. Tyro-3 family receptors are essential regulators of mammalian spermatogenesis. (1999) Nature. 398(6729):723-8. DOI: 10.1038/19554

Krappa, R., Nguyen, A., Burrola, P., Deretic, D., Lemke, G. Evectins: vesicular proteins that carry a pleckstrin homology domain and localize to post-Golgi membranes. (1999) Proceedings of the National Academy of Sciences of the United States of America. 96(8):4633-8.

Zorick, T.S., Syroid, D.E., Brown, A., Gridley, T., Lemke, G. Krox-20 controls SCIP expression, cell cycle exit and susceptibility to apoptosis in developing myelinating Schwann cells. (1999) Development. 126(7):1397-406.

Syroid, D.E., Zorick, T.S., Arbet-Engels, C., Kilpatrick, T.J., Eckhart, W., Lemke, G. A role for insulin-like growth factor-I in the regulation of Schwann cell survival. (1999) Journal of Neuroscience. 19(6):2059-68.

Lemke, G., Barde, Y.A. Neuronal and glial cell biology. (1998) Current Opinion in Neurobiology. 8(5):567-569.

Désarnaud, F., Do Thi, A.N., Brown, A.M., Lemke, G., Suter, U., Baulieu, E.E., Schumacher, M. Progesterone stimulates the activity of the promoters of peripheral myelin protein-22 and protein zero genes in Schwann cells. (1998) J. Neurochem. 71(4):1765-8.

Zhao, J.J., Lemke, G. Selective disruption of neuregulin-1 function in vertebrate embryos using ribozyme-tRNA transgenes. (1998) Development. 125(10):1899-907.

Zhao, J.J., Lemke, G. Rules for ribozymes. (1998) Molecular and Cellular Neurosciences. 11(1-2):92-7. DOI: 10.1006/mcne.1998.0669

Lemke, G. Eph receptors and ligands in axon pathway choice, target recognition, and synaptogenesis. (1998) Progress in Brain Research. 117:171-6. DOI: https://doi.org/10.1016/S0079-6123(08)64015-7

Brown, A.M., Lemke, G. Multiple regulatory elements control transcription of the peripheral myelin protein zero gene. (1997) Journal of Biological Chemistry. 272(46):28939-47.

Lemke, G. A coherent nomenclature for Eph receptors and their ligands. (1997) Molecular and Cellular Neurosciences. 9(5-6):331-2. DOI: 10.1006/mcne.1997.0630

Maycox, P.R., Ortuño, D., Burrola, P., Kuhn, R., Bieri, P.L., Arrezo, J.C., Lemke, G. A transgenic mouse model for human hereditary neuropathy with liability to pressure palsies. (1997) Molecular and Cellular Neurosciences. 8(6):405-16. DOI: 10.1006/mcne.1997.0600

Gassmann, M., Lemke, G. Neuregulins and neuregulin receptors in neural development. (1997) Current Opinion in Neurobiology. 7(1):87-92.

Zorick, T.S., Lemke, G. Schwann cell differentiation. (1996) Current Opinion in Cell Biology. 8(6):870-6.

Syroid, D.E., Maycox, P.R., Burrola, P.G., Liu, N., Wen, D., Lee, K.F., Lemke, G., Kilpatrick, T.J. Cell death in the Schwann cell lineage and its regulation by neuregulin. (1996) Proceedings of the National Academy of Sciences of the United States of America. 93(17):9229-34.

Zorick, T.S., Syroid, D.E., Arroyo, E., Scherer, S.S., Lemke, G. The Transcription Factors SCIP and Krox-20 Mark Distinct Stages and Cell Fates in Schwann Cell Differentiation (1996) Molecular and Cellular Neurosciences. 8(2/3):129-45. DOI: 10.1006/mcne.1996.0052

Zorick, T.S., Syroid, D.E., Arroyo, E., Scherer, S.S., Lemke, G. The transcription factors SCIP and Krox-20 mark distinct stages and cell fates in Schwann cell differentiation. (1996) Molecular and Cellular Neurosciences. 8(2-3):129-45. DOI: 10.1006/mcne.1996.0052

Lemke, G. Neuregulins in development. (1996) Molecular and Cellular Neurosciences. 7(4):247-62. DOI: 10.1006/mcne.1996.0019

Kilpatrick, T.J., Brown, A., Lai, C., Gassmann, M., Goulding, M., Lemke, G. Expression of the Tyro4/Mek4/Cek4 gene specifically marks a subset of embryonic motor neurons and their muscle targets. (1996) Molecular and Cellular Neurosciences. 7(1):62-74. DOI: 10.1006/mcne.1996.0005

Gassmann, M., Casagranda, F., Orioli, D., Simon, H., Lai, C., Klein, R., Lemke, G. Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. (1995) Nature. 378(6555):390-4. DOI: 10.1038/378390a0

Weinstein, D.E., Burrola, P.G., Lemke, G. Premature Schwann cell differentiation and hypermyelination in mice expressing a targeted antagonist of the POU transcription factor SCIP. (1995) Molecular and Cellular Neurosciences. 6(3):212-29. DOI: 10.1006/mcne.1995.1018

Stitt, T.N., Conn, G., Goret, M., Lai, C., Bruno, J., Radzlejewski, C., Mattsson, K., Fisher, J., Gies, D.R., Jones, P.F., Masiakowski, P., Ryan, T.E., Tobkes, N.J., Chen, D.H., DiStefano, P.S., Long, G.L., Basilico, C., Goldfarb, M.P., Lemke, G., Glass, D.J., Yancopoulos, G.D. The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases. (1995) Cell. 80(4):661-670. DOI: 10.1016/0092-8674(95)90520-0

Plantinga, L.C., Schrama, L.H., Eggen, B.J., Gispen, W.H., Verhaagen, J., Lemke, G. B-50/GAP-43 mRNA expression in cultured primary Schwann cells is regulated by cyclic AMP. (1994) Neuroreport. 5(18):2465-8.

Lai, C., Gore, M., Lemke, G. Structure, expression, and activity of Tyro 3, a neural adhesion-related receptor tyrosine kinase. (1994) Oncogene. 9(9):2567-78.

Messing, A., Behringer, R.R., Wrabetz, L., Hammang, J.P., Lemke, G., Palmiter, R.D., Brinster, R.L. Hypomyelinating peripheral neuropathies and schwannomas in transgenic mice expressing SV40 T-antigen. (1994) Journal of Neuroscience. 14(6):3533-9.

Lai, C., Lemke, G. Structure and expression of the Tyro 10 receptor tyrosine kinase. (1994) Oncogene. 9(3):877-83.

Monuki, E.S., Kuhn, R., Lemke, G. Cell-specific action and mutable structure of a transcription factor effector domain. (1993) Proceedings of the National Academy of Sciences of the United States of America. 90(21):9978-82.

Lemke, G. Transcriptional regulation of the development of neurons and glia. (1993) Current Opinion in Neurobiology. 3(5):703-8.

Monuki, E.S., Kuhn, R., Lemke, G. Repression of the myelin P0 gene by the POU transcription factor SCIP. (1993) Mech. Dev. 42(1-2):15-32.

Lemke, G. The molecular genetics of myelination: an update. (1993) Glia. 7(4):263-71. DOI: 10.1002/glia.440070402

Weinmaster, G., Roberts, V.J., Lemke, G. Notch2: a second mammalian Notch gene. (1992) Development. 116(4):931-41.

Lemke, G., Kuhn, R., Monuki, E.S., Weinmaster, G. Expression and activity of the transcription factor SCIP during glial differentiation and myelination. (1991) Ann. N. Y. Acad. Sci. 633:189-95. DOI: https://doi.org/10.1111/j.1749-6632.1991.tb15609.x

Spreyer, P., Kuhn, G., Hanemann, C.O., Gillen, C., Schaal, H., Kuhn, R., Lemke, G., Müller, H.W. Axon-regulated expression of a Schwann cell transcript that is homologous to a 'growth arrest-specific' gene. (1991) EMBO Journal. 10(12):3661-8.

Nave, K.A., Lemke, G. Induction of the myelin proteolipid protein (PLP) gene in C6 glioblastoma cells: functional analysis of the PLP promotor. (1991) Journal of Neuroscience. 11(10):3060-9.

Weinmaster, G., Roberts, V.J., Lemke, G. A homolog of Drosophila Notch expressed during mammalian development. (1991) Development. 113(1):199-205.

Kuhn, R., Monuki, E.S., Lemke, G. The gene encoding the transcription factor SCIP has features of an expressed retroposon. (1991) Molecular and Cellular Biology. 11(9):4642-50.

Lai, C., Lemke, G. An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system. (1991) Neuron. 6(5):691-704.

Lemke, G., Kuhn, R., Monuki, E.S., Weinmaster, G. Transcriptional controls underlying Schwann cell differentiation and myelination. (1990) Ann. N. Y. Acad. Sci. 605:248-53. DOI: https://doi.org/10.1111/j.1749-6632.1990.tb42397.x

Monuki, E.S., Kuhn, R., Weinmaster, G., Trapp, B.D., Lemke, G. Expression and activity of the POU transcription factor SCIP. (1990) Science. 249(4974):1300-3.

Messing, A., Behringer, R.R., Slapak, J.R., Lemke, G., Palmiter, R.D., Brinster, R.L. Insertional mutation at the ld locus (again!) in a line of transgenic mice. (1990) Mouse Genome. 87:107.

Weinmaster, G., Lemke, G. Cell-specific cyclic AMP-mediated induction of the PDGF receptor. (1990) EMBO Journal. 9(3):915-20.

Kuhn, R., Pravtcheva, D., Ruddle, F., Lemke, G. The gene encoding peripheral myelin protein zero is located on mouse chromosome 1. (1990) Journal of Neuroscience. 10(1):205-9.

Monuki, E.S., Weinmaster, G., Kuhn, R., Lemke, G. SCIP: a glial POU domain gene regulated by cyclic AMP. (1989) Neuron. 3(6):783-93.

Lemke, G. Unwrapping the genes of myelin. (1988) Neuron. 1(7):535-43.

Lemke, G., Chao, M. Axons regulate Schwann cell expression of the major myelin and NGF receptor genes. (1988) Development. 102(3):499-504.

Lemke, G., Lamar, E., Patterson, J. Isolation and analysis of the gene encoding peripheral myelin protein zero. (1988) Neuron. 1(1):73-83.

Webster, H.F., Lamperth, L., Favilla, J.T., Lemke, G., Tesin, D., Manuelidis, L. Use of a biotinylated probe and in situ hybridization for light and electron microscopic localization of Po mRNA in myelin-forming Schwann cells. (1987) Histochemistry. 86(5):441-4.

Lemke, G., Axel, R. Isolation and sequence of a cDNA encoding the major structural protein of peripheral myelin. (1985) Cell. 40(3):501-8.

Lemke, G.E., Brockes, J.P. Identification and purification of glial growth factor. (1984) Journal of Neuroscience. 4(1):75-83.

Lemke, G.E., Brockes, J.P. Glial growth factor: a mitogenic polypeptide of the brain and pituitary. (1983) Fed. Proc. 42(9):2627-9.

Brockes, J.P., Fryxell, K.J., Lemke, G.E. Studies on cultured Schwann cells: the induction of myelin synthesis, and the control of their proliferation by a new growth factor. (1981) Journal of Experimental Biology. 95:215-30.

Brockes, J.P., Lemke, G.E., Balzer, D.R. Purification and preliminary characterization of a glial growth factor from the bovine pituitary. (1980) Journal of Biological Chemistry. 255(18):8374-7.

Miao, S., Fourgeaud, L., Burrola, P.G., Stern, S., Zhang, Y., Happonen, K.E., Novak, S.W., Gage, F.H., Lemke, G. Tyro3 promotes the maturation of glutamatergic synapses. (n.d.) Frontiers in Neuroscience. 18:1327423. DOI: 10.3389/fnins.2024.1327423